Although Ginkgo biloba is commonly used to improve memory and cognition, a recent human trial suggests that it may not slow age-related mental decline.
The Ginkgo Evaluation of Memory (GEM) study included 3,069 community-dwelling older adults (72-96 years old) who had normal cognition or mild cognitive impairment. The participants were randomly assigned to receive 120 milligrams of a ginkgo extract or placebo twice daily for an average of 6.1 years.
The authors measured cognitive function using the Modified Mini-Mental State Examination (3MSE) and the cognitive subscale of the Alzheimer Disease Assessment Scale (ADAS-Cog). Memory, attention, visual-spatial construction, language and executive functions were rated based on the sums of the individual tests.
The authors found that ginkgo supplementation did not result in significantly less cognitive decline compared to placebo.
For more information about ginkgo, please visit Natural Standard's Foods, Herbs & Supplements database.
References
1.Natural Standard: The Authority on Integrative Medicine. http://www.naturalstandard.com/
2.Snitz BE, O'Meara ES, Carlson MC, et al. Ginkgo biloba for Preventing Cognitive Decline in Older Adults: A Randomized Trial. JAMA. 2009;302:2663-70.
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