Continued from Yesterday
An increase in weight by 5 kg increases the risk of cardiovascular disease by 30-50%. A person with a BMI of 33 kglm2 has a 320% greater risk of cardiovascular disease compared to a person with a BMI of23 kg/m2 (Anderson et al. 2003). Cardiovascular disease is responsible for 70-80% of the deaths in diabetic individuals, and weight loss is well documented to reduce cardiovascular risk factors. The increase in diabetes and its associated risk of cardiovascular disease represents a serious economic threat. The direct and indirect costs of diabetes to the United States are over $100 billion per year, a number that is sure to rise, and despite the extent of the problem in the United States, developing countries with far less resources are being hardest hit (American Diabetes Association 1998).
If the impending global catastrophe of diabetes and cardiovascular disease is to be averted, along with the suffering and economic challenges that it entails, type 2 diabetes must be prevented. The mainstay in the treatment of obesity has been diet and lifestyle treatment. This chapter reviews the efficacy of diet and lifestyle in preventing diabetes and the potential for pharmacological approaches to act as adjunctive measures.
Diet and Lifestyle
There have been several major studies evaluated diet and lifestyle change to prevent diabetes and all have come to similar conclusions. These important studies will be reviewed over the next several days.
Continued Tomorrow
Source: Nutraceuticals, Glycemic Health and Type 2 Diabetes
Frank Greenway, MD
Chapter 3
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