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Thursday, December 2, 2010

Dangerous Spin Doctors #2

Mark Hyman November 29

The Danger of “Evidence-Based” Medicine

“Evidence-based” medicine is considered the highest standard of care and is advocated as the basis for all decision making in medical schools and academic centers. The idea is that we must make decisions based on sound medical evidence. That sounds good in theory, but it only works if that evidence can be trusted; if the evidence at hand has been generated independently, without bias and with the sole desire to find the best treatments—pharmaceutical or otherwise. This model fails to work if the underlying motive is profit.

In a recent report in the Journal of the American Medical Association French scientists reviewed over 600 studies published in the top medical journals during an entire year, and analyzed in detail 72 of those they considered to be of the highest quality. In their analysis they only included studies with the most respected and reliable design—the randomized controlled trial. The authors of this report did not just read the abstracts and conclusions of the studies they reviewed, but independently analyzed the raw data. Their findings call into question the reliability of the very scientific papers that doctors use to make decisions regarding treatment and that the press counts on to communicate the latest medical findings.

They found that 40 percent of the articles misrepresented the data in the abstract or in the main text of the study. Furthermore they uncovered that in cases where studies had negative outcomes —in other words, the treatment studied DID NOT work—the scientists authoring the studies created a “spin” on the data that showed the treatments DID work. Here is their conclusion:

“In this representative sample of RCT’s (randomized controlled trials) published in 2006 with statistically non-significant primary outcomes, the reporting and interpretation of findings was frequently inconsistent with the results.”

In plain language, 40 percent of the studies we count on to make medical decisions are authored by scientists who act as “spin doctors” distorting medical research to suit personal needs or corporate economic interests. “Spin” can be defined as specific reporting that could distort the interpretation of results and mislead readers. If the conclusions in 40 percent of the papers published in medical journals are being spun toward independent interests, how can we consider the medicine we are practicing “evidence based?”

Consider the example of the recent large and widely quoted JUPITER trial “proving” that Crestor (a statin or cholesterol-lowering drug) could prevent heart attacks in people with normal or low cholesterol.(ii) In this trial researchers twisted the data to suit the commercial sponsor of the study. An independent review of the JUPITER trial published in the Archives of Internal Medicine showed that it was deeply flawed and the actual data did NOT show any benefit for the prevention of heart disease.(iii) If this were an isolated incident, we could overlook it.

Unfortunately, it’s a consistent pattern.

http://www.drfranklipman.com/dangerous-spin-doctors-7-steps-to-protect-yourself-from-deception-in-medical-research/

http://www.depsyl.com/

http://back2basicnutrition.com/

http://bionutritionalresearch.olhblogspace.com/

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