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Monday, December 27, 2010

What is Nail-Patella syndrome?














Diseases of the Nails #10

Nail-patella syndrome is an autosomal dominant condition characterized by nail dysplasia (shown), patellar aplasia-hypoplasia, elbow arthrodysplasia, and iliac horns. The nails may be absent, hypoplastic, or dystrophic with ridges, pits, and/or triangular lunulae. The anomalies are typically symmetric with the thumbs most severely affected and decreased severity progressing towards the fifth digit. Anomalies are evident at birth. Patients may also suffer from proteinuria, glaucoma, attention-deficit/hyperactivity disorder, recurrent dislocations, and irritable bowel syndrome. Treatment is aimed at pain management, physical therapy, and controlling renal failure. No specific therapy is available for the nail anomalies.

http://www.medscape.com/features/slideshow/nail-diseases?src=nl_slide

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