Is Reversal of Pre-Diabetes Possible?

Diagnosis and Possible Reversal of Pre-Diabetes

Comprehensive Supplementation is a Key to Successful Treatment

At least 92% of diabetes cases can be attributed to lifestyle choices, with 8% attributable to genetics. The fact is, diabetes is extremely expensive, can be very deadly, and is almost completely avoidable. Pre-diabetes (PD) is the antecedent to diabetes. The causes of pre-diabetes are:

· lack of an essential nutrient,
· environmental toxin exposure,
· distress that impairs stress responsive hormones and neuro­-chemicals,
· autoimmune attack on the insulin production centers or insulin receptors, and
· being sedentary

The consequences of PD range from obesity to insulin resistance, also known as metabolic syndrome and syndrome X. The health rami­fications of unmanaged PD that leads to diabetes include heart attacks, coronary artery atherosclerosis, arteriosclerosis, and stroke.

I will use a recent successful outcome study in pre-diabetes that I had the opportunity to lead as an example of what can be done using an innovative comprehensive approach.1

The goals of our study were to improve sugar insulin performance and remove obstacles to recovery. This meant that we wanted to reduce the glucose/insulin ratio to healthier levels. We also wanted to confirm this by reduction in hemoglobin A1c as an independent risk marker. Because of the role of stress hormones in PD risk, we also measured cortisol and DHEA stress hormones to assess how they changed over the six weeks of the program. We are highly encouraged that all markers improved and the improvement was statistically significant. Statistically, we found significance below the 0.001 level. This makes the outcome highly likely to be real and unlikely to be due to coinci­dence. We were also pleased to report that compliance was high and dropout rates below expectation.

In the outcome study, we

· restored tolerance in the immune defense and repair system;
· corrected essential nutrient deficits;
· improved detoxification of environmental toxins;
· reduced excess distress and restored neurohormone balance; and
· identified deficits in digestion or other systems and improve function, structure and resilience.

The following supplements proved effective in this program:

1. Novel nutrients and herbs in standardized form in 100% rice bran oil with phosphatides to improve uptake and components that improve insulin function:

· Chromium as citrate 250–1,000 mcg/day
· Vanadium ascorbate 250–1,000 mcg/day
· French lilac (Galega) 150–600 mg/day
· Bitter melon (Marah) 150–600 mg/day
· Huckleberry/Bilberry 100–400 mg/day
· Agnus Castus•• 250–1,000 mg/day

2. L-carnitine as the fumarate, 500–2,500 mg/day; GABA, 200–1,000 mg/day; and alginate, 50–250 mg/day in MCT oil for better uptake.
3. Fully buffered 100% L-ascorbate with potassium, calcium, magne­sium, and zinc.
4. Polyphenolics as quercetin dihydrate 250–5,000 mg/day and soluble OPC 5–100 mg/day.
5. Exercise in the form of walking measured with a pedometer with the goal of 10,000 steps per day.
6. Stress management, mindfulness, and relaxation response prac­tices, 20 minutes twice daily.
7. Good hydration based on drinking at least eight 8-ounce glasses of water daily, sufficient to stimulate 3 to 6 urinations per day.

Our successful outcome study in people with PD confirms the hope that people can feel and function better at lower net costs when enough of the essential protective and repair factors are provided.

http://www.naturalmedicinejournal.com/pdf/NMJ_OCT09_CR.pdf

http://www.depsyl.com/

http://back2basicnutrition.com/

http://bionutritionalresearch.olhblogspace.com/