An extract from the seeds of the common ash tree (Fraxinus excelsior) may improve glucose (blood sugar) levels in healthy volunteers, according to a study by University of Toronto scientists.
In the study, 16 adults were given 50 grams of glucose to increase their blood sugar levels. Then the participants were randomly assigned to take 1 gram of an ash seed extract (Fraxipure®) or a placebo.
Fasting blood glucose levels were measured immediately before supplementation. Postprandial plasma glucose levels were then measured 15, 30, 45, 60, 90 and 120 minutes after supplementation. Postprandial plasma insulin levels were measured 30, 60, 90 and 120 minutes after supplementation.
The participants then switched groups, and the experiment was repeated.
Compared to the placebo, Fraxipure® significantly lowered the incremental postprandial plasma glucose concentrations 45 minutes and 120 minutes after glucose administration. It also prompted a significant secretion of insulin (which regulates blood glucose) 90 minutes after glucose administration. The participants reported no adverse effects.
The researchers called for longer-term studies to evaluate the efficacy and safety of the ash seed extract in healthy and diabetic individuals and also to explore possible mechanisms of action.
Some supplements that have already been studied for their ability to lower blood sugar in people with type 2 diabetes include alpha-lipoic acid, beta-glucan, ginseng and gymnema.
For more information about treating diabetes, please visit Natural Standard's Medical Conditions database.
References
1.Natural Standard: The Authority on Integrative Medicine. http://www.naturalstandard.com/
2.Visen P, Saraswat B, Visen A, et al. Acute effects of Fraxinus excelsior L. seed extract on postprandial glycemia and insulin secretion on healthy volunteers. J Ethnopharmacol. 2009 Nov 12;126(2):226-32. View Abstract
http://www.ncbi.nlm.nih.gov/pubmed/19723572?dopt=Abstract
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